Abstract
The features of surgical treatment of patients with carotid stenosis on the background of diabetes mellitus were studied. From 2015 to 2019 in the Department of Acute Vascular Diseases, State Institution «IONKh named after V.T. Zaitsev NAMNU» 299 carotid endarterectomies were performed (in 245 men and 54 women). Patients were divided into two groups (with and without diabetes). Diabetes mellitus was observed in 76 patients of the second group. There are no significant differences in significant postoperative complications in patients with diabetes and without it; in patients with diabetes, one stroke was noted in the postoperative period. At a five-year follow-up, severe restenosis (more than 50 %) occurred in 14 patients with diabetes mellitus and in 46 patients without diabetes. In diabetes mellitus, a lesion of the internal carotid artery is more pronounced, which manifests itself in an increase in the length of the plaque and severe calcification, which requires a direct endarterectomy with latching. It was shown that multifocal intracranial stenosis is determined in patients with diabetes mellitus according to computed tomography data, which increases the risk of stroke, and the peculiarity endothelial lesions leads to an increase in the frequency of restenosis.
References
Akbari C.M., Pomposelli F.B., Gibbons G.W., Campbell D.R., Freeman D.V., LoGerfo F.W. (1997). Diabetes mellitus: a risk factor for carotid endarterectomy? J. Vasc. Surg., vol. 25, pp. 1070–1076.
Halm E.A., Hannan E.L., Rojas M., Tuhrim S., Riles T.S., Rockman C.B., Chassin M.R. (2005). Clinical and operative predictors of outcomes of carotid endarterectomy. J. Vasc. Surg., vol. 42, issue 3, pp. 420–428.
Kannel W.B., McGee D.L. (1979). Diabetes and cardiovascular disease: the Framingham study. JAMA, vol. 241, issue 19, pp. 2035–2038.
Salenius J.P., Harju E., Riekkinen H. (1990). Early cerebral complication in carotid endarterectomy: risk factors. J. Cardiovasc. Surg. (Torino), vol. 31, issue 2, pp. 162–167.
Stoner M.C., Abbott W.M., Wong D.R., Hua H.T., Lamuraglia G.M., Kwolek C.J. et al. (2006). Defining the high-risk patient for carotid endarterectomy: an analysis of the prospective National Surgical Quality Improvement Program database. J. Vasc. Surg., vol. 43, issue 2, pp. 285–295.
Tuomilehto J., Rastenyte D., Jousilahti P., Sarti C., Vartiainen E. (1996). Diabetes mellitus as a risk factor for death from stroke. Prospective study of the middle-aged Finnish population. Stroke, vol. 27, issue 2, pp. 210–215.
Kuusisto J., Mykkänen L., Pyörälä K., Laakso M. (1994). Non-insulin dependent diabetes and its metabolic control are important predictors of stroke in elderly subjects. Stroke, vol. 25, issue 6, pp. 1157–1164.