Features of diagnosis of polyomavirus infection in renal transplant recipients
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Keywords

chronic kidney disease
kidney transplantation
BK-poliomavirus infection
cyclosporine A
tacrolimus

How to Cite

Zheleznikova, M. (2020). Features of diagnosis of polyomavirus infection in renal transplant recipients. Medicine Today and Tomorrow, 79(2), 83–87. Retrieved from https://msz.knmu.edu.ua/article/view/318

Abstract

The incidence of BK-poliomavirus infection was studied in the first year of the posttransplant period, taking into account the nosological forms and the influence of immunosuppressors. Forty six recipients of renal transplant were examined, 7 (15.21 %) cases of viruria and 5 (10.86 %) cases of viremia of BK-poliomavirus were revealed. Viremia and viruria was significantly higher in patients receiving tacrolimus than in patients in the scheme of immunosuppressive drugs is cyclosporine A. There was a significant increase in the incidence of viruria in transplanted patients with diabetes mellitus during the first year after operation. The conversion of immunosuppressive therapy from cyclosporine to tacrolimus can be recommended to improve graft survival in the posttransplant period.

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