Abstract
Superior Sagittal Sinus (SSS) meningiomas present a particular surgical challenge due to their close proximity to vital venous structures. Although microsurgical resection remains the primary treatment method, the use of adjuvant radiosurgery is becoming increasingly important in cases of incomplete (subtotal) tumor resection. The study aimed to investigate the modalities of surgical treatment for SSS meningiomas and to substantiate the rationale for radiosurgical treatment. The study included 68 patients operated on between 2019 and 2024. Total resection of the SSS meningioma (Simpson grade I–II) was performed in 49 patients (72%), while 19 patients (28%) underwent subtotal resection with a residual tumor component left in the SSS lumen. The study was conducted in compliance with bioethical principles, specifically the World Medical Association's Declaration of Helsinki (1964–2024), and was approved by the Ethics Committee of the State Institution "Romodanov Institute of Neurosurgery of the National Academy of Medical Sciences of Ukraine" (Protocol No.5, December 13, 2017), with informed consent obtained from all patients. Among early complications in patients after total SSS resection, the following were recorded: paraplegia in 2 cases (3%), tetraplegia in 1 (1%), structural secondary generalized epilepsy in 1 (1%), and venous infarction in 1 (1%). The 6-month Magnetic Resonance Imaging follow-up revealed no continued growth of the tumor or residual elements of the SSS meningioma in any of the patients. It was concluded that microsurgical resection remains the main treatment method for SSS meningiomas, ensuring a high rate of recurrence-free periods in patients. Combined treatment, including microsurgery and radiosurgery, demonstrated its effectiveness in preserving patients' quality of life, reducing the risks of tumor recurrence and severe postoperative complications.
Keywords: venous drainage, thrombosis, postoperative complications, recurrence-free survival.
References
Ostrom QT, Cioffi G, Gittleman H, Patil N, Waite K, Kruchko C, Barnholtz-Sloan JS. CBTRUS Statistical Report: Primary Brain and Other Central Nervous System Tumors Diagnosed in the United States in 2012-2016. Neuro Oncol. 2019;21(Suppl_5):v1-100. DOI: 10.1093/neuonc/noz150. PMID: 31675094.
Wang B, Zhang GJ, Wu Z, Zhang JT, Liu PN. Surgical outcomes and prognostic factors of parasagittal meningioma: a single-center experience 165 consecutive cases. Br J Neurosurg. 2022;36(6):756-61. DOI: 10.1080/02688697.2020.1867825. PMID: 33423566.
Fokas E, Henzel M, Surber G, Hamm K, Engenhart-Cabillic R. Stereotactic radiation therapy for benign meningioma: long-term outcome in 318 patients. Int J Radiat Oncol Biol Phys. 2014;89(3):569-75. DOI: 10.1016/j.ijrobp.2014.02.042. PMID: 24751409.
Magill ST, Theodosopoulos PV, McDermott MW. Resection of falx and parasagittal meningioma: complication avoidance. J Neurooncol. 2016;130(2):253-62. DOI: 10.1007/s11060-016-2283-x. PMID: 27778211.
Taori S, Wei Z, Hadjipanayis CG, Niranjan A, Lunsford LD. Long-term outcomes following upfront single-session gamma knife stereotactic radiosurgery for large volume meningiomas. J Neurooncol. 2025;173(2):429-38. DOI: 10.1007/s11060-025-05000-5. PMID: 40163246.
Pinzi V, Fariselli L, Marchetti M, Scorsetti M, Navarria P. Stereotactic Radiotherapy for Parasagittal and Parafalcine Meningiomas: Patient Selection and Special Considerations. Cancer Manag Res. 2019;11:10051-60. DOI: 10.2147/CMAR.S187371. PMID: 31819638.
Weil CR, Rock CB, Sarkar V, Gravbrot N, Lew FH, Rock CB, et al. Lack of Impact of Expansion Size from Gross Tumor Volume to Planning Target Volume on Control Rates and Patterns of Recurrence in Fractionated Radiotherapy for WHO Grade 1 Meningiomas. Am J Clin Oncol. 2025;48(8):403-9. DOI: 10.1097/COC.0000000000001193. PMID: 40266822.
Travis R, Taylor M, Willey C, Bredel M, Riley KO, Markert JM, Fiveash J. Assessment of Local and Regional Control in High-Risk Atypical (WHO Grade 2) Meningiomas Receiving Stereotactic Fractionated Radiosurgery. Cureus. 2025;17(1):e77322. DOI: 10.7759/cureus.77322. PMID: 39944442.

This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.
