Clinical characteristics of the dental status of patients with red lichen planus of the mucous membrane of the oral cavity
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Keywords

red lichen planus
dermatosis
precancer

How to Cite

Bozhyk , S. (2021). Clinical characteristics of the dental status of patients with red lichen planus of the mucous membrane of the oral cavity. Medicine Today and Tomorrow, 90(3), 82-90. https://doi.org/10.35339/msz.2021.90.3.boz

Abstract

The development of lichen planus (RLP) is associated with the action of various toxins, allergens, infectious agents, and disorders of the immune system. The aim of the work was to study the dental status of patients with RLP, its role in the development and course of the disease, and the impact on treatment outcomes. A clinical dental examination was carried out in 37 patients, including 31 women (83.78% of those examined) aged 33–65 years; 6 men 16.22%, aged 23 to 52 years. By the time of the initial visit, indicators of the intensity and prevalence of caries, the presence of non-carious lesions, dentoalveolar anomalies and deformities, hygienic and periodontal indicators were recorded. Dental deformities and anomalies of the soft tissues of the oral cavity were diagnosed in 59.46% of all examined patients of both sexes, wedge-shaped defects – in 24.32% of all examined patients of both sexes, pathological wear – in 18.92% of all examined patients. The intensity of caries was 7.89±0.46. The Green-Vermillion hygiene index was (2.13±0.05) points. The prevalence of inflammatory and dystrophic-inflammatory changes in periodontal tissues at the time of the initial examination at the dentist was (83.78±6.39) %, which allows us to state a high degree of compromise of periodontal tissues. The papillary-marginal-alveolar index (PMA) was (26.95±2.70) %, which corresponds to moderate gingivitis, and the Muhlemann-Saxer papillary bleeding index (PBI) was (1.40±0.14) points. The results obtained regarding the age and sex distribution of patients with RLP agree with the developments of foreign scientists of recent years, indicating a high activity of the manifestation of this disease in women of perimenopausal age, in particular, endocrine changes in women, especially in the production of sex steroids. The presence of aggravated dental status is a local risk factor and serves as a mechanism that activates etiological factors and intensifies already existing changes. The results obtained indicate the need to develop a complex of professional and individual oral hygiene in patients with RLP, as well as the relationship between their dental status and changes in the oral mucosa.

Keywords: red lichen planus, dermatosis, precancer.

https://doi.org/10.35339/msz.2021.90.3.boz
PDF (Українська)

References

Brodovska N. The dynamics of clinical and specific immunological indicators in patients with lichen planus in the process of complex treatment. Journal of dermatovenerology and kosmetology n. N.A. Torsuev. 2018;2:6–15. Available from: http://nbuv.gov.ua/UJRN/jdkit_2018_2_3

Brodovska N, Denysenko О, Perepichka М. Incidence of lichen ruber planus in inhabitants of Chernivtsi region (Northern Bukovyna). Journal of dermatovenerology and kosmetology n. N.A. Torsuev. 2018;1:42–8. Available from: http://nbuv.gov.ua/UJRN/jdkit_2018_1_8

Lucchese A, Di Stasio D, Romano A, Fiori F, De Felice GP, Lajolo C, et al. Correlation between Oral Lichen Planus and Viral Infections Other Than HCV: A Systematic Review. J Clin Med. 2022;11(18):5487. DOI: 10.3390/jcm11185487. PMID: 36143134.

Ishkov MO, Karavan JaR. The case of the erosive oral lichen planus. Clinical & Experimental Pathology. 2019:18(1):153–5. Available from: http://cep.bsmu.edu.ua/article/view/1727-4338.XVIII.1.68.2019.26

Kolenko YG, Timokhina TO, Lynovytska OV, Mialkivskyi KO, Khrol NS. Epidemiological situation of pre-cancer diseases of the oral mucous in Ukraine. Wiad Lek. 2022;75(6):1453–8. DOI: 10.36740/WLek202206105. PMID: 35907215.

Cai X, Zhang J, Zhang H, Li T. Overestimated risk of transformation in oral lichen planus. Oral Oncol. 2022;133:106025. DOI: 10.1016/j.oraloncology.2022.106025. PMID: 35858493.

Palaniappan P, Baalann KP. Erosive oral lichen planus. Pan Afr Med J. 2021;40:73. DOI: 10.11604/pamj.2021.40.73.26013. PMID: 34804341.

Tampa M, Caruntu C, Mitran M, Mitran C, Sarbu I, Rusu LC, et al. Markers of Oral Lichen Planus Malignant Transformation. Dis Markers. 2018;2018:1959506. DOI: 10.1155/2018/1959506. PMID: 29682099.

Olejnik M, Jenerowicz D, Adamski Z, Czarnecka-Operacz M, Dorocka-Bobkowska B. The prevalence of contact hypersensitivity in patients with oral lichen planus. Postepy Dermatol Alergol. 2022;39(4):668–74. DOI: 10.5114/ada.2021.107549. PMID: 36090725.

Melnyk TV, Bondar SA. Influence of complex therapy on indicators of markers of oxidative stress in patients with lichen ruber planus. Ukrainian journal of dermatology, venereology, cosmetology. 2019;2(73):45–9. Available from: https://journals.indexcopernicus.com/api/file/viewByFileId/678015.pdf

Sundararajan A, Muthusamy R, Gopal Siva K, Harikrishnan P, Kumar SCK, Rathinasamy SK. Correlation of Mast Cell and Angiogenesis in Oral Lichen Planus, Dysplasia (Leukoplakia), and Oral Squamous Cell Carcinoma. Rambam Maimonides Med J. 2021;12(2):e0016. DOI: 10.5041/RMMJ.10438. PMID: 33938803.

Chiang CP, Yu-Fong Chang J, Wang YP, Wu YH, Lu SY, Sun A. Oral lichen planus - Differential diagnoses, serum autoantibodies, hematinic deficiencies, and management. J Formos Med Assoc. 2018;117(9):756–65. DOI: 10.1016/j.jfma.2018.01.021. PMID: 29472048.

Raj AT, Patil S. Diagnostic flaws in oral lichen planus and related lesions. Oral Oncol. 2017;74:190–1. DOI: 10.1016/j.oraloncology.2017.10.003. PMID: 28993107.

Melnik TV, Bondar SA, Gavrilyuk AO. Modern pathogenetic aspects and methods of lichen planus treatment. Reports of Vinnytsia National Medical University. 2017;2(21):553–7. Available from: https://reports-vnmedical.com.ua/index.php/journal/article/view/57/50

Kolomiets, SV, Udaltsova KO, Shynkevich VI. Recommendations for tactics in the detection of potentially malignant lesions in the oral cavity. Ukrainian dental almanac. 2018;1:75–8. Available from: https://dental-almanac.org/index.php/journal/article/view/313/311

Nakaz MOZ Ukrainy No.499 vid 10.08.2011 " Pro deyaki pytannya orhanizatsiyi pratsi likariv-stomatolohiv". [Order of the Ministry of Health of Ukraine No.499 on 10 Aug 2011 "About some issues of organization of work of dental doctors"]. Valid on 2022 [in Ukrainian]. URL: https://zakon.rada.gov.ua/rada/show/v0499282-11#Text

Nakaz MOZ Ukrainy No.566 on 23.11.2004 "Pro zatverdzhennia protokoliv nadannia medychnoi dopomohy za spetsialnostiamy "ortopedychna stomatolohiia", "terapevtychna stomatolohiia", "khirurhichna stomatolohiia", "ortodontiia", "dytiacha terapevtychna stomatolohiia", "dytiacha khirurhichna stomatolohiia" [Order of the Ministry of Health of Ukraine No.566 on 23 Nov 2004 "On the approval of protocols for the medical care provision in the specialties "orthopedic dentistry", "therapeutic dentistry", "surgical dentistry", "orthodontics", "children's therapeutic dentistry", "children's surgical dentistry"]. Valid on 2022 [in Ukrainian]. Available from: https://is.gd/hO1eev

Kutsevlyak VF, Lakhtin YuV. Indeksna otsinka parodontalʹnoho statusu: navchalʹnyy posibnyk. 2-he vyd., pererob. i dop. [Index assessment of periodontal status: study guide. 2nd ed., revision. and additional]. Sumy: publishing and production enterprise "Mriya"; 2015. 104 p. [in Ukrainian]. Available from: https://essuir.sumdu.edu.ua/bitstream-download/123456789/41768/1/stomatology.pdf

Thongprasom K. Oral lichen planus: Challenge and management. Oral Dis. 2018;24(1–2):172–3. DOI: 10.1111/odi.12712. PMID: 29480607.

Mohan RPS, Gupta A, Kamarthi N, Malik S, Goel S, Gupta S. Incidence of Oral Lichen Planus in Perimenopausal Women: A Cross-sectional Study in Western Uttar Pradesh Population. J Midlife Health. 2017;8(2):70–4. DOI: 10.4103/jmh.JMH_34_17. PMID: 28706407

Gupta A, Mohan RP, Gupta S, Malik SS, Goel S, Kamarthi N. Roles of serum uric acid, prolactin levels, and psychosocial factors in oral lichen planus. J Oral Sci. 2017;59(1):139–46. DOI: 10.2334/josnusd.16-0219. PMID: 28367894.