Differential-diagnostic criteria of active ulcerative colitis and irritable bowel syndrome
Vol 90 No 1 (2021), Therapy
Vol 90 No 1 (2021)

Differential-diagnostic criteria of active ulcerative colitis and irritable bowel syndrome

Therapy
https://doi.org/10.35339/msz.2021.90.01.04
Published March 31, 2021
P.P. Snisarevskyi
Shupyk National Healthcare University of Ukraine, Kiev
https://orcid.org/0000-0002-4454-3678
O.O. Dyadyk
Shupyk National Healthcare University of Ukraine, Kiev
https://orcid.org/0000-0002-9912-4286
A.E. Dorofeyev
Shupyk National Healthcare University of Ukraine, Kiev
https://orcid.org/0000-0003-4280-1474
T.P. Snisarevska
Shupyk National Healthcare University of Ukraine, Kiev
https://orcid.org/0000-0003-3931-2848
PDF (Українська)

How to Cite

Snisarevskyi, P., Dyadyk, O., Dorofeyev, A., & Snisarevska, T. (2021). Differential-diagnostic criteria of active ulcerative colitis and irritable bowel syndrome. Medicine Today and Tomorrow, 90(1), 33-43. https://doi.org/10.35339/msz.2021.90.01.04
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Abstract

In press

The authors conducted a comparative analysis of clinical, laboratory and endoscopic data of 80 patients with ulcerative colitis (UC) of the 1st, 2nd, 3rd degrees of activity and 82 patients with irritable bowel syndrome (IBS) to determine the possible differential-diagnostic criteria of these diseases. It has been found that UC of the 1st, 2nd, 3rd degrees of activity develops with equal frequency among men and women, but IBS develops more often in women. The average age of patients with UC [the 1st degree of activity – (49.1±1.8) years, the 2nd degree of activity – (49.2±1.9) years, the 3rd degree of activity – (49.4±2.5) years] is higher compared to the average age of patients with IBS [(38.4±1.2) years]. UC of the 1st, 2nd, 3rd degrees of activity more often develops in patients after 40 years, while IBS in patients at the age of 18 till 40 years. Pain along the intestine occurs with equal frequency in patients with UC of the 2nd and 3rd degrees of activity. Stool disorders occur with equal frequency in patients with UC of the 1st, 2nd, 3rd degrees of activity and IBS. In a clinical blood test with the same frequency diagnose anemia and increased erythrocyte sedimentation rate in patients with UC of the 2nd and 3rd degrees of activity. Increased level of fecal calprotectin is documented with equal frequency in patients with UC of the 1st, 2nd, 3rd degrees of activity. Bleeding in the large intestine is a characteristic endoscopic finding for patients with UC of the 3rd degree of activity. Erosive-ulcerative changes in the large intestine on endoscopic examination are found with equal frequency in patients with UC of the 1st, 2nd, 3rd degrees of activity. The comparative analysis of clinical, laboratory and endoscopic data in most cases did not allow to identify the clear differential-diagnostic criteria for different degrees of activity of UC, UC and IBS. The data obtained by the authors update the conduct of a comprehensive morphological study, which would identify the specific and clear differential-diagnostic criteria of UC and IBS, which will certainly improve the treatment and diagnostic process among this category of patients and also diseases prognosis.

Keywords: differential-diagnostic criteria, active ulcerative colitis, irritable bowel syndrome.

https://doi.org/10.35339/msz.2021.90.01.04
PDF (Українська)

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