The role of fetal microchimerism in the development of complications in pregnant women with autoimmune thyroid disease
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Keywords

autoimmune thyroiditis
pregnancy
hormones
placental insufficiency

How to Cite

Scherbakov, A., & MіelikovaT. (2020). The role of fetal microchimerism in the development of complications in pregnant women with autoimmune thyroid disease. Medicine Today and Tomorrow, 71(2–3), 61–67. Retrieved from https://msz.knmu.edu.ua/article/view/435

Abstract

This аrticle will provide an overview of a novel phenomenon in medicine known as microchimerism. Microchimerism is defined as the long-term presence of genetically distinct populations of cells in peripheral blood and tissues of individual. This condition may be caused by the transplacental bidirectional cell trafficking between mother and fetus during pregnancy. Microchimerism has been suggested to play a key role in the pathogenesis of autoimmune diseases. The review presents modern data on etiology and the role of autoimmune thyroiditis microchimerism. We present a comprehensive assessment of the positive and negative impact on the body of the microchimerism -media owner, and the influence of other endogenous and exogenous factors in the pathogenesis of autoimmune thyroiditis.

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