Keywords
hypertension
systemic inflammation
interleukin-18
interleukin-10
echocardiography
How to Cite
Abstract
Chronic obstructive pulmonary disease (COPD) is often combined with hypertension (HT) and contribute to maintaining persistent systemic inflammation. Levels of interleukin-18 (IL-18) and interleukin-10 (IL-10) in systemic blood flow were analyzed at patients with COPD in combination with HT, their significant increase compared to practically healthy and patients with isolated COPD was revealed. Reliable correlations between excessive content of the studied cytokines and hemodynamic parameters have been established, which may indicate the role of IL-18 and IL-10 in the genesis of structural and functional myocardial changes.
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