Keywords
neonatal period
glutamyl transferase
lactate dehydrogenase
How to Cite
Abstract
The study involved evaluation of lactate dehydrogenase and γ-glutamyltransferase levels at postnatal adaptation stage in order to establish the effect of myocardial cellular energy-deficiency on cardiovascular system state in full-term and pre-term infants. The study implied examination of 120 newborns, 60 of them were pre-term infants (Group I) and 60 healthy full-term newborns (Group II). According to Doppler echocardiography 60.0 % of pre-term infants were found to have morphological and functional disorders of the cardiovascular system. Group I was shown to include 43.3 % of infants with hypokinetic type of central hemodynamics. Lactate dehydrogenase level in the first day of life in this category of patients was (955.55±272.08) U/l, during the second week of life it was (627.0±153.85) U/l; glutamyltransferase level was (78.71±47.43) U/l and (77.27±43.22) U/l, respectively. The state of diastolic function of the heart ventricles in newborns in the early neonatal period depends on the level of glutamyltransferase and lactate dehydrogenase.
References
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