Morphological features of parathyroide glands of white rats after immunostimulation
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Keywords

parathyroid gland
rats
morphometry
immunostimulation
immunostimulant

How to Cite

Erokhina, V. (2020). Morphological features of parathyroide glands of white rats after immunostimulation. Medicine Today and Tomorrow, 75(2), 4–10. Retrieved from https://msz.knmu.edu.ua/article/view/355

Abstract

The features of the morphometric parameters of the parathyroid glands of white rats were studied after the use of the derivative of the thymic hormone arginyl-asparagill-lysyl-valile-tyrosyl-arginine (AALVTA). The study was carried out on 48 male rats of reproductive age with an initial body weight (180±10) g. Animals were injected by immunostimulant on 50 mg/kg for the 1st, 3rd, 5th, 7th, 9th days. Intact rats served as control. The animals were brought out the experiment on the 3rd, 15th, 30th and 90th day after the completion of the injection. The linear parameters of the parathyroid glands (thickness, width, height), the area of the organ in the sections, the number of blood vessels in the field of vision of the slide and their diameter were estimated, the thickness of the capsular gland was measured. It was found that after the introduction of AALVTA there is a significant increase in the morphometric parameters of the glandular glands on 7, 15 and 30 days after the immune stimulation, which may indicate a high morphoreactivity of the organ. On 90th days the data are closer to the control values, which may indicate the compensatory and adaptive nature of the reaction in response to exogenous factor.

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