Abstract
In press
Background. Optimization of combat surgical trauma management, particularly timely amputation and subsequent prosthetics, is a relevant task of wartime medicine.
Aim. To analyze the full cycle of treatment and rehabilitation of a patient with severe combined blast injury of both lower limbs using a clinical case example, focusing on a multidisciplinary approach and quality of life assessment.
Materials and Methods. A clinical case of treatment of a 42-year-old serviceman with open comminuted fractures of both lower leg bones and feet, as well as blast injury to the chest and abdomen, is presented. Clinical examination data, radiological studies, and dynamic observation were used. The patient's condition was assessed using the Glasgow Coma Scale. Treatment effectiveness and quality of life were evaluated using the Ukrainian version of the standardized EuroQol EQ-5D-5L questionnaire. The study did not receive targeted support in the form of grants from public or private foundations, it was carried out as a private initiative of the authors.
Research Ethics. The study was conducted in accordance with the principles of the World Medical Association Declaration of Helsinki (1964–2024). The patient provided informed voluntary consent for the use of his anonymized medical data for scientific analysis and publication. The research algorithm and methods were approved by the local ethics commission.
Results. The initial treatment strategy included intensive therapy, antibiotic prophylaxis, primary surgical debridement, VAC (Vacuum-Assisted Closure) therapy, and osteosynthesis with external fixation devices. On day 18, a purulent complication (S. aureus) developed, with a predicted unfavorable outcome for preserving the right limb. After discussion with the patient, amputation of the right lower leg was performed. Rehabilitation at a specialized center included physiotherapy, therapeutic exercises, orthotic support for the left limb, and prosthetic fitting for the right. Assessment with the EQ-5D-5L on day 134 showed significant limitations (profile 21212, index 8), while after 12 months, significant improvement was recorded (profile 11110, index 4).
Conclusions. This clinical case demonstrates that the success in managing severe blast injuries is based on a multidisciplinary approach, timely application of modern surgical technologies (VAC therapy, external fixation), timely and justified decision-making for amputation when the prognosis is unfavorable, and subsequent comprehensive rehabilitation with prosthetics. This algorithm allows not only saving the patient's life but also ensuring a high level of functional recovery and quality of life.
Keywords: orthopedics and traumatology, combat surgical trauma, amputation, quality of life, EQ-5D, medical rehabilitation.
References
Qureshi MK, Ghaffar A, Tak S, Khaled A. Limb salvage versus amputation: a review of the current evidence. Cureus. 2020;12(8):e10092. DOI: 10.7759/cureus.10092. PMID: 33005513.
Sayer NA, Chiros CE, Sigford B, Scott S, Clothier B, Pickett T, Lew HL. Characteristics and rehabilitation outcomes among patients with blast and other injuries sustained during the Global War on Terror. Arch Phys Med Rehabil. 2008;89(1):163-70. DOI: 10.1016/j.apmr.2007.05.025. PMID: 18164349.
Teasdale G, Jennett B. Assessment of coma and impaired consciousness. A practical scale. Lancet. 1974;2(7872):81-4. DOI: 10.1016/s0140-6736(74)91639-0. PMID: 4136544.
van Reenen M, Janssen B, Stolk E, Secnik Boye K, Herdman M, Kennedy-Martin M, et al. (eds.). EQ-5D-5L User Guide. Version 4.0. Rotterdam: EuroQol Research Foundation; 2025. 42 p. Available at: https://euroqol.org/information-and-support/documentation/user-guides
Ministry of Health of Ukraine. Order No. 400 of 12 May 2010 "On approval of the State sanitary norms and rules "Hygienic requirements for drinking water intended for human consumption", in force of 20 Sep 2025. Verkhovna Rada (Parliament) of Ukraine. Legislation of Ukraine. Available at: https://zakon.rada.gov.ua/laws/show/z0452-10 [in Ukrainian].
State sanitary norms of microclimate of industrial premises, approved by Resolution of the Chief State Sanitary Doctor of Ukraine No.42 of 01 Dec 1999, in force of 20 Sep 2025. Verkhovna Rada (Parliament) of Ukraine. Legislation of Ukraine. Available at: https://zakon.rada.gov.ua/rada/show/va042282-99 [in Ukrainian].
The EuroQol Group. EuroQol – a new facility for the measurement of health-related quality of life. Health Policy. 1990;16(3):199-208. DOI: 10.1016/0168-8510(90)90421-9. PMID: 10109801.
The EuroQol Group. EuroQol – a new facility for the measurement of health-related quality of life. Health Policy. 1990;16(3):199-208. DOI: 10.1016/0168-8510(90)90421-9. PMID: 10109801.
Devlin NJ, Brooks R. EQ-5D and the EuroQol Group: Past, Present and Future. Appl Health Econ Health Policy. 2017;15(2):127-37. DOI: 10.1007/s40258-017-0310-5. PMID: 28194657.
Kim J, Choi W, Cho W, Moon J. Impact of delayed amputation on clinical outcomes compared to that of early amputation in patients with blunt polytrauma. Sci Rep. 2025;15:8184. DOI: 10.1038/s41598-025-93322-9. PMID: 40065089.
Bharadwaj S, Balasubramanian S. Limb Salvage Versus Amputation: A Review of Variables Influencing the Assessment and Decision-Making in Complex Limb Fracture Management. Cureus. 2024;16(11):e74322. DOI: 10.7759/cureus.74322. PMID: 39720385.

This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.
