Dental biofilm: control of formation, disorganization and means of regulation
PDF (Українська)

Keywords

microorganisms
оral cavity
biofilm
hygiene

How to Cite

Zabolotna, I. (2023). Dental biofilm: control of formation, disorganization and means of regulation. Medicine Today and Tomorrow, 92(2), 40-46. https://doi.org/10.35339/msz.2023.92.2.zab

Abstract

Biofilm is a predominant growth form of a greater number of microorganisms in the oral cavity that has the differences in physiology and genetics compared to planktonic forms. It requires a review of methods of the diagnostics and management of patients with the diseases caused by dental biofilms. The literature review was conducted with the aim of summarizing modern scientific information related to the control of its formation and evaluation of means for disorganization and regulation that are used in clinical dentistry. Based on the results of these studies a close relationship between the level of hygiene and the microbiological state of the oral cavity has been justified. Carrying out individual and professional hygiene is an important component in the comprehensive treatment of dental patients. It has been proven that the pathogenicity of the dental biofilm can be significantly reduced by breaking the integrity of its structure and restoring the normal microflora with the help of high-quality professional hygiene. But long-term uncontrolled use of personal hygiene products can cause some changes in the quality of the microbiome of the oral cavity. Modern research is aimed at disorganization of the biofilm matrix by pharmaceutical and non-pharmacological means. But its destruction can lead to the release of living microorganisms and the dissemination of the pathogen. The presented results of the use of different groups of means for normalizing the microflora of the oral cavity have both advantages and disadvantages that requires further discussion. Qualitative control over the development of dental biofilm will permit to anticipate the course of teeth diseases and periodontal tissues, and objectively assess the effectiveness of the prescribed treatment. Conducting a microbiological study of the biocenosis of the oral cavity will be the basis for choosing personal hygiene products and implementing timely measures. All this will further contribute to increase in the efficiency of prevention and management of pathology of the teeth.

Keywords: microorganisms, оral cavity, biofilm, hygiene.

https://doi.org/10.35339/msz.2023.92.2.zab
PDF (Українська)

References

Vodoriz YY, Ilenko NM, Ilenko NV, Petrushanko TO. Features of dental status and some microbiological parameters of the oral cavity of young men. Ukrainian Dental Almanac. 2015;4:13-6. Available at: http://nbuv.gov.ua/UJRN/Usa_2015_4_5 [in Ukrainian].

Sidashenko OI, Voronkova OS, Sirokvasha EA, Vinnikov AI. Bioplivka yak osoblyva forma orhanizatsiyi bakteriy ta yiyi rol v infektsiynikh protsesakh [Biofilm as a Spesial Form of Bacteria and its Role in Infectious Processes]. Bulletin of problems in bioigy and medicine. 2013;3(2):36-41. Available at: http://nbuv.gov.ua/UJRN/Vpbm_2013_3%282%29__9 [in Ukrainian].

Boychenko OM, Kotelevska NV, Nikolishin AK, Zaitsev AV. Morphofunctionality of dental plaque. Bulletin of problems in bioigy and medicine. 2016;4,2(134):9-15. Available at: http://nbuv.gov.ua/UJRN/Vpbm_2016_4%282%29__3

Nedashkivska VV, Dronova ML, Vrynchanu NO. Biofilms and their role in infectious diseases. Ukrainian Scientific Medical Youth Journal. 2016;4(98):10-9. Available at: https://mmj.nmuofficial.com/index.php/journal/article/view/85 [in Ukrainian].

Worthington HV, MacDonald L, Poklepovic Pericic T, Sambunjak D, Johnson TM, Imai P, Clarkson JE. Home use of interdental cleaning devices, in addition to toothbrushing, for preventing and controlling periodontal diseases and dental caries. Cochrane Database Syst Rev. 2019;4(4):CD012018. DOI: 10.1002/14651858.CD012018.pub2. PMID: 30968949

Toncheva KD. Biofilm in dentistry. Actual problems of modern medicine: Bulletin of Ukrainian Medical Stomatological Academy. 2015;15(4):338-43. Available at: http://nbuv.gov.ua/UJRN/apsm_2015_15_4_80 [in Ukrainian].

Bhole SS, Vibhute NA, Belgaumi U, Kadashetti V, Bommanavar S, Kamate W. Effect of an educational intervention on manual toothbrush bristle wear: A light microscopic study. J Indian Soc Periodontol. 2022;26(6):604-8. DOI: 10.4103/jisp.jisp_50_21.

Akifusa S, Isobe A, Kibata K, Oyama A, Oyama H, Ariyoshi W, Nishihara T. Comparison of dental plaque reduction after use of electric toothbrushes with and without QLF-D-applied plaque visualization: a 1-week randomized controlled trial. BMC Oral Health. 2020;20(1):4. DOI: 10.1186/s12903-019-0982-3. PMID: 32008572.

Lee ES, de Josselin de Jong E, Kim BI. Detection of dental plaque and its potential pathogenicity using quantitative light-induced fluorescence. J Biophotonics. 2019;12(7):e201800414. DOI: 10.1002/jbio.201800414. PMID: 30834691.

de Alencar CR, de Oliveira GC, Tripodi CD, Gonçalves PS, Ionta FQ, Honorio HM, et al. Dental Plaque Disclosing as an Auxiliary Method for Professional Dental Prophylaxis in Early Childhood. Int J Clin Pediatr Dent. 2019;12(3):189-93. DOI: 10.5005/jp-journals-10005-1617. PMID: 31708613.

Faustova MO, Nazarchuk OA. Influence of modern antiseptics on biofilm formation by gram-negative pathogens during infectious and inflammatory complications after dental implants placement. Actual problems of modern medicine: Bulletin of Ukrainian Medical Stomatological Academy. 2018;18,1(61):200-4. Available at: http://nbuv.gov.ua/UJRN/apsm_2018_18_1_46 [in Ukrainian].

James P, Worthington HV, Parnell C, Harding M, Lamont T, Cheung A, et al. Chlorhexidine mouthrinse as an adjunctive treatment for gingival health. Cochrane Database Syst Rev. 2017;3(3):CD008676. DOI: 10.1002/14651858.CD008676.pub2. PMID: 28362061.

Divnych TY. Correction of changes of the oral cavitys microflora depends upon the duration of removable dentures use. Ukrainian Dental Almanac. 2015;4:47-9. Available at: http://nbuv.gov.ua/UJRN/Usa_2015_4_12 [in Ukrainian].

Romanova YuH [inventors]. Patent Ukrainy na vynakhid No.59013 "Sposib pidvyshchennya efektyvnosti protezuvannya u patsiyentiv z dysbiozom porozhnyny rota" [Patent of Ukraine for the invention No.59013 "Method of increasing the effectiveness of prosthetics in patients with oral cavity dysbiosis"]. Romanova YuH, owner. Started to act оn 26 Apr 2011, validity is terminated. Ukrpatent, Bull. No.8. Available at: https://is.gd/JBynMu [in Ukrainian].

Bila NF, Shnaider SA, Safchuk KI, Safarova LZ. Determination of the effect of higienic rinses of various compositions on the state of the oral cavity microflora. Bulletin of Dentistry. 2022;45(3):6-8. DOI: 10.35220/2078-8916-2022-45-3.2 [in Ukrainian].

Kostenko О, Krivtsova М, Kostenko Е, Savchuk О. Analysis of the dominant microbial associations of the cavity of the mouth and especially their sensitivity to antibacterial drugs. Actual dentistry. 2018;5:40-3. Available at: https://is.gd/7sqUKO [in Ukrainian].

Oktysiuk YuV. Prevention of Dental Caries in Children as a Fundamental Success of General Dental Health of the Population. Ukrainian Journal of Medicine, Biology and Sport. 2018;3(1):235-40. DOI: 10.26693/jmbs03.01.235 [in Ukrainian].

Alharbi MS, Alshehri FA, Alobaidi AS, Alrowis R, Alshibani N, Niazy AA. High molecular weight hyaluronic acid reduces the growth and biofilm formation of the oral pathogen Porphyromonas gingivalis. Saudi Dent J. 2023;35(2):141-6. DOI: 10.1016/j.sdentj.2023.01.008. PMID: 36942200.

Blinder OO, Blinder OV, Rotar DV, Humenna AV. Dynamics of methicillin-resistant staphylococcus aureus prevalence among patients of the Chernivtsi region. Zaporozhye medical journal. 2022;24(4):454-8. DOI: 10.14739/2310-1210.2022.4.254912 [in Ukrainian].

Loban HA. Оral cavity is the ecological niche of microorganisms community. Biology and Ecology. 2015;1(1):84-9. Available at: http://nbuv.gov.ua/UJRN/biolecol_2015_1_1_12 [in Ukrainian].

Abou Neel EA, Aljabo A, Strange A, Ibrahim S, Coathup M, Young AM, Bozec L, Mudera V. Demineralization-remineralization dynamics in teeth and bone. Int J Nanomedicine. 2016;11:4743-3. DOI: 10.2147/IJN.S107624. PMID: 27695330.

Cannon M, Trent B, Vorachek A, Kramer S, Esterly R. Effectiveness of CRT at measuring the salivary level of bacteria in caries prone children with probiotic therapy. J Clin Pediatr Dent. 2013;38(1):55-60. DOI:10.17796/jcpd.38.1.b481624264142082.

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